Back, Back, Back
Jul. 14th, 2025 09:59 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
And then it was off to watch the Home Run Derby, which was an impressive display of power with yet another new set of rules. This year's rules worked reasonably well, I think. :)
Club Query, A Shadowrun Place
Jul. 15th, 2025 01:59 am![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
People still enjoy the challenge of testing themselves and their knowledge and ability to learn, yes, the humble quiz still has its adherents, followers, and teams. Game shows, pub quizzes, and trivia games are still popular.
The Space:
Club Query is just outside of Downtown Seattle proper, but is still in what is recognized as the Downtown district. The club takes up the lower two floors of Sprang and Finger Office Building, replacing a previous restaurant that had failed. The twelve floors above are a mixture of professional offices including the law firm of Gorshin, Nygma, and Radox. The exterior is unremarkable, fronted with stone and windows of one-way glass (so the patrons can look out, unobserved). A schedule of events and their menu is posted, physically and in AR, by the front door. There is also a subtle members-only entrance through the elevator lobby that whisks people to the upper floors.
The interior is well, but not excessively, lit with clean, modernist lines and decoration. It has an aura of efficiency to the layout and design which is instinctively noticeable. The decorations are memorabilia from famous game shows and classic puzzles, with crossword puzzles being common. The main floor is broken up into the bar, the main dining area, and the event room. The event room can be reconfigured for various competitions and has theme nights for various games and competitions. As they take cheating very seriously at Club Query, the entire event room can be severed from the Matrix by use of a Faraday cage woven into the building structure.
The upper floor, unusually, has the kitchen and several private rooms, each named and themed after famous quiz shows (such as the Jeopardy Room and the Mastermind Suite), they are unusual in advertising the fact that each room can be cut off locally from the Matrix through use of an installed Faraday cage, again part of their commitment to fair play.
Membership in Club Query gets the member priority seating and the ability to reserve spots for the major quizzes.
The waitstaff uniforms consist of black pants or skirt, white shirt, and black waistcoat. Their order pads have non-volatile memory to take orders while within a Faraday cage. There are efficient and carefully trained not to provide hints or advice to the patrons.
The Food and Drink:
Club Query’s food, as far as main courses, is consistently competent, but rarely rises to the heights of culinary excellence. It is more renowned for the clever design of its meals which imply a puzzle to be solved (and usually are). But their desserts are justly famous both as puzzles and culinary delights.
The Club’s bartenders and drink selection are both top-notch, though heavily leaning into theme cocktails. They have a selection of extremely expensive liquors for discerning, and well-heeled, patrons.
Entertainment:
Guess. Every night is Quiz Night at Club Query, sometimes themed; there is a weekly Jeopardy-themed night for example. But every night hosts at least one Quiz Night, some open, some members only, but the quizzes are the big draw. They often have, usually local, celebrities to act as the Master of Ceremonies or Quizmasters.
Occasionally, they run other puzzle or mental challenges. They have a bimonthly crossword challenge, jigsaw puzzle nights, and other such but never to the detriment of the quiz nights.
Staff and Regulars:
Club Query is owned. indirectly by the partners of Gorshin, Nygma and Radox. They purchased the space when the previous restaurant went bankrupt and turned it into the sort of place they wanted to spend their afterwork hours in. The club and its management is through a trust, so that G, N and R have no direct influence on the day-to-day running of the business, this is so that workers (and partners) of G, N and R can compete in the quizzes with no accusations of cheating or favorism.
Edward Astin is the Club’s manager, brought in from New York just for this job. He has exceeded expectations managing the difficult balancing act of getting more people in which still maintaining an aura of exclusiveness around the club. Mister Astin, as he prefers to be addressed on duty, lets everything run, only appearing to assist and make sure that things move smoothly. He has a sixth sense for problems before they start and intervenes before they become problems. Astin is surprisingly competent in an absurdly wide variety of skills and everyone who works at the club has a story of him stepping up and solving a minor problem using skills that no one knew he had and moving on. Astin is of average size but remarkably athletic; he is always well-dressed with perfect hair and a pencil mustache. [Connection 4]
The chief quizmaster is Mary “Riddle Girl” Ross, member of MENSA at six, started college at sixteen, graduated with a Math PhD at twenty-one, and currently works at the Comprehensive Field Unification Association, attempting to mathematically model mana flows. But her important work is designing the Master Quiz for Club Query. She checks all of the official quizzes and trains the quizmasters, wanting consistency for the players. Mary is fascinated by all kinds of puzzles and riddles and is happy to talk about such at great length. She is an athletic young woman with auburn hair and grey eyes. [Connection 4]
The primary dessert chef is Sindara “Cinnamon” Yamara-Rich, a short elf woman who specializes in complex and creative desserts. She enjoys working for Club Query as let her experiment and build unusual desserts. Cinnamon wears her blond hair in a long braid, pinned up while she is working, and favors bright colors when off-duty. She occasionally works with an alchemist who specializes in baked goods for some of her masterpieces. Cinnamon is always interested in learning new baking and decorating techniques. [Connection 3]
Naturally, more staff is needed to run the Club, waitstaff, kitchen staff, chefs, bartenders, tech support, and security. The Club Query shares a security contract with the Sprang and Finger Office Building with Minutemen Security.
Campaign uses:
The Club is a great place to meet if you need to be in a public place and under a Faraday cage, just meet quietly.
Club Query is also used as a place to hire specialists for various tasks as its meeting rooms all include Faraday cages and a wide range of people come to the Club. So even strange specialists may not stand out as much.
If you need to meet a contact, or make a contact, who enjoys quizzes, you will not find a better place than Club Query to do so.
If you need to impress someone with an unusual cake, perhaps one that will convey a message that will only make sense to the person it is sent to. A dessert by Cinnimon might be able to make just what you need (or direct you to someone who can).
Notes: This was the location of the meet for the last game I ran, it had no existence before then, but I am very pleased with how it is turning out. Several in-jokes and references here, which may or may not be picked up by my group. If anyone else gets them, I will be amazed and I will award you a No-Prize of your very own.
Images Bild von Tumisu auf Pixabay and used under their license.
Computers, do computer things better!
Jul. 14th, 2025 09:00 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
I love YouTube Music — it's a great streaming system and gives me access to music that I could only have dreamed of when I was younger. But there's one thing about it — a small thing really, but still big enough that it bothers me: When you have a playlist, it should be a trivial thing for the software to add up the running times of all the songs in the playlist and give you a runtime for the playlist, and this works for shorter playlists, but once a playlist reaches 5 hours or more in length, the program gets lazy and anything over 5 hours is either "5+ hours" or "5 hours [XX] minutes," where [XX] isn't the actual number of minutes past 5 hours, instead the point after 5 hours where the software got lazy and decided to stop adding. Not a deal killer, not even that big of a deal, really, but it's annoying.
New Hires Must Have Laser Focus
Jul. 15th, 2025 12:00 am![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read New Hires Must Have Laser Focus
I'm a department manager, just back from a two-week holiday. In my absence a slew of new starters have joined and today is their first day unsupervised on the checkouts.
Me: *To another manager.* "I wonder if this new lot are going to be decent, or will they be as dumb as the last batch?"
Don’t Be Alarmed When The Place Gets Robbed
Jul. 14th, 2025 10:00 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read Don’t Be Alarmed When The Place Gets Robbed
The unit I am renting is on the first floor, the landlord, whose main job is bank director, lives above me and has a terrace which his family enjoys in the summer. My windows open in the light well. Most of the time, I only get to hear his teenage son singing along to his favourite rapper in the same way a drunken sailor would try to sing along to a crooner in some shady speakeasy down the harbour, but not this time.
No One Here Is Kidding
Jul. 14th, 2025 08:00 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Boss: "[Coworker], you said you had two sons."
Coworker: "That's right."
Boss: "Didn't you say you were going to bring them?"
Coworker: "I did!"
Boss: "Wonderful! Where are they?"
Coworker: "Under my desk?"
Sulfonate Esters in Drug Substances: Real Problem or Not?
Jul. 14th, 2025 03:41 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
You of course want to be attentive to the possibility of forming toxic impurities during the manufacture of pharmaceuticals, and there are many regulatory and analytical checkpoints designed for this. One example that’s become much better-known in recent years is the formation of nitrosamines that can be traced back to synthesis steps taking place in (relatively) high-temperature DMF and similar solvents.
Another one that’s probably only known to certain groups is the possibility of sulfonate ester formation. Sulfonate esters are used as reactive leaving groups in organic chemistry (mesylates and tosylates are two widely-known examples), and their electrophilic nature makes them something that you will want to minimize your exposure to. The related sulfate esters (such as the prototype dimethyl sulfate) are indeed toxic from several directions (acutely and longer-term mutagenically), and methyl mesylate itself, while less acutely hazardous, will also alkylate DNA with alacrity and is considered a carcinogen. What’s probably the hottest of all of these reagents, methyl fluorosulfonate, is so acutely dangerous that it dropped out of industrial production entirely. It used to be sold as “Magic Methyl”, because it would indeed slap a methyl group on most anything that could accept one, but spilling it outside a fume hood could be fatal due to its profoundly irritating effects on lung tissue.
So I think everyone is in agreement that we don’t want sulfonate esters lacing the drug supply. But how many examples of that are known? This recent paper notes that many regulatory authorities require extra caution and analysis when a drug substance containing a free OH group is reacted with a sulfonic acid, under the assumption that small amounts of such esters could be formed. But mechanistically that doesn’t make much sense: you need strenuously acidic conditions for that to happen, and that’s not what’s going on when you make sulfonate salts of amine-containing drugs. And that salt formation is why you’d be running this step in the first place - you form more-soluble salts of those amines for a better formulation, in the same way that you see hydrochlorides, acetates, phosphates, citrates and other such derivatives in dosage forms. We don’t worry about stray OH groups being turned into alkyl chlorides when an HCl salt is formed, and formation of a sulfonate ester under similar conditions is just as (un)likely. Indeed, the paper just cited notes this fallacy with respect to the regulatory treatment of hydrobromide salts.
But as it shows, there are many literature citations that warn about this potential reaction, even though none of them actually point at a real example. In fact, there don’t appear to be any. The closest case is a 2007 incident with contaminated nelfinavir (Viracept), which did indeed have ethyl mesylate in it. The drug itself was a methanesulfonate salt, but the problem turned out not to be formation of the ester during salt formation - the mesylate ester was in the acid reagent from the start! It has been stored for months in a tank that had been cleaned with ethanol and never dried, and that will indeed give you some ester formation (because the pH is so low, conditions that just don’t obtain during pharmaceutical salt formation). The author of the new paper refers to the regulatory reports that appeared after this incident as “highly misleading” on this point and says that the European Department of the Quality of Medicines in particular has “for many years supported a policy on alkyl-sulfonate impurities that is contradicted by mechanistic and experimental evidence”.
So let’s see if anything comes of this gauntlet being thrown down! I’ll report back, but don’t expect anything to happen at any noticeable speed. . .
Why Do I Love Charts? Let Me Count the Ways.
Jul. 14th, 2025 02:14 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)

Charts hold back chaos, and we should sing their praises!
Why Do I Love Charts? Let Me Count the Ways.
Bundle of Holding: Hearts of Wulin
Jul. 14th, 2025 02:08 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)

This new Hearts of Wulin Bundle presents Hearts of Wulin, the tabletop roleplaying game of Chinese wuxia action melodrama from Age of Ravens Games.
Bundle of Holding: Hearts of Wulin
Be Quiet, Or The Drama Will Become A Murder Thriller
Jul. 14th, 2025 05:55 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read Be Quiet, Or The Drama Will Become A Murder Thriller
My coworker is a drama magnet; she always has a problem with someone and wants to include anyone and everyone who will listen to her complain. Today, she is mad at her sister for not answering her phone. We are about to start a meeting when she sits beside me.
It’s Raining Cats And Dogs And HR Violations
Jul. 14th, 2025 04:00 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read It’s Raining Cats And Dogs And HR Violations
Eavesdropping Coworker: "Wait, did you say you had dogs?"
Coworker: "Yes, I have two."
Eavesdropping Coworker: "And you're going to get rid of them… right?"
Coworker: "Uh… no? Why would I do that?"
...of Podcasts and Such
Jul. 14th, 2025 09:05 am![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
Speaking of podcasts, I had a very odd interaction with a potential panelist on a panel I proposed for Diversicon. I've been, as you know, gentle reader, fairly obsessed with doing programming committee work for a completely DIFFERENT covention, and so I haven't much talked about the fact that I will be one of the Guests of Honor at Diversicon 32, along with Naomi Kritzer. Diversicon is a local to me (Minneapolis/St. Paul, MN) convention and is coming up soon! September 5-7!
So, what happened was this: I got an email from someone in programming connecting me with a potential panelist. The initial email was very straight-forward. This person has been writing radio plays for a podcast down in Florida called the Radio Theatre Project. Sounds like a decent fit, right? But, this person added this to their communication with me, "I'd be happy to talk to Lyda and come up with a presentation" (emphasis mine). I wrote back and said, "Sure! I'm happy to try to figure out a way to combine our similar expertise into a panel of some sort. My podcast isn't fiction and I do none of the technical aspects of recording, editing, or producing it, but I'm sure there are some commonalities."
Immediately the other panelist seemed to want to back off, however. They talked about how "my audience" might not be interested in the things they were doing and that the two types of writing were fundamentally different. I acknowledged that, but tried to encourage this person, anyway, by saying that, yes, that's true, but podcasts are a thing in general and I'm happy to spend some time on the panel talking about the things they do and the things I do. This seemd to mollify this person, briefly.
BUT then they proposed getting together for a coffee to hammer out our "presentation" or to at least come up with talking points.
I have to admit, y'all? I was very confused by the continued use of the world presentation.
I had to write back and say, "It's a panel discussion, right? Something informal and off-the-cuff?" I told them I am always happy to pre-consider questions that might highlight this or that, but, like, this is one of those situations, I thought, where "this meeting could be an email." I did, however, try to say this kindly and suggest that while I was not against getting together for a coffee, per se, a panel discussion (if that's what we were having) wasn't probably worthy of something so intense.
I guess I pissed his person off somehow? I didn't mean to!
But, surprise, surprise, this person has now declined the offer to be on the panel with me. Which would be FINE, except for the fact that they felt the need to leave with this parting shot: "I listened to your MLOP 27: American Flagg podcast about cyberpunk. It is very focused and detailed. It offered a wealth of information for fans of serious science fiction. I'm not a serious sci-fi fan. I don't have the background and experience to speak about this kind of podcast. I've also found the easiest way to kill the humor in almost anything is to analyze it."
Like, is that directed at me? Or is this person saying that they don't want to analyze their own humor for fear of destroying the fun in it? (Their radio plays are humorous, apparently.) I decided to go with the latter, because it does no good to make enemies in a convention pool as small as Diversicon's. So, I told them how sorry I was that they have chosen to opt out and hoped that we could at least meet and chat at the con.
But the entire exchange was so baffling, you all. I know this person at least a little. Their name is familiar to me. They are NOT a stranger to the local science fiction and fantasy scene. They know what SFF convention panels are. The fact that they kept calling it a presentation has actually made me a little terrified that I'm actually going to be the ONLY person on this panel. SHOULD I BE PREPARING A LECTURE/PRESENTATION????? I am now a little fearful that maybe I should be!
I wouldn't be paranoid about this, but this has happened to me in the past.
I once proposed a panel for (I think) MarsCON about manga and manhwa and, when I arrived at the convention and got my hands on the program booklet, I discovered that I was, in fact, the only person talking about this subject FOR AN HOUR. Luckily, in that case, it wasn't until the next day and someone (Anton, probably,) had asked me if I needed any technical support for my panel/presentation and I said, "Okay, yes? Gimme some way to run a powerpoint presentation," and I went home that night and MADE ONE UP. I think I had exactly 5 people in the audience, but they were happy to see the covers of some titles I recommended, etc.
JFC.
If it is just me... what am I going to talk about for an hour by myself about podcasts? I mostly listen to fiction podcasts, but if people are there, as this proposed panelist suggested for my particular podcast, I don't know that there's enough to actually say about what it is that we do. I mean, Ka!lban does most of the hard work and I just show up and talk about whatever it is we've chosen as a topic. That's it. That's my entire experience. I don't know how this could possibly fill an hour!
I guess I'll find out!
Another Win For The Olympics
Jul. 14th, 2025 01:30 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read Another Win For The Olympics
Younger Man: *Calmly.* "It's really not seen as taboo anymore. It's basically wearable art. I can show you the piece I've designed with the artist."
Older Gentleman: "I don't care. I keep telling you, tattoos are classless and ridiculous. How will anybody take you seriously? You'll look like a thug!"
Clarke Award Finalists 2005
Jul. 14th, 2025 10:27 am![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
Which 2005 Clarke Award Finalists Have You Read?
Iron Council by China Miéville
10 (32.3%)
Cloud Atlas by David Mitchell
10 (32.3%)
Market Forces by Richard Morgan
5 (16.1%)
River of Gods by Ian McDonald
9 (29.0%)
The System of the World by Neal Stephenson
13 (41.9%)
The Time Traveler's Wife by Audrey Niffenegger
10 (32.3%)
Bold for have read, italic for intend to read,, underline for never heard of it.
Which 2005 Clarke Award Finalists Have You Read?
Iron Council by China Miéville
Cloud Atlas by David Mitchell
Market Forces by Richard Morgan
River of Gods by Ian McDonald
The System of the World by Neal Stephenson
The Time Traveler's Wife by Audrey Niffenegger
2025.07.14
Jul. 14th, 2025 08:16 am![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
Ripples in space-time from collision recorded by gravitational wave detector forces a rethink of how the objects form
Ian Sample Science editor
https://www.theguardian.com/science/2025/jul/14/scientists-detect-biggest-ever-merger-of-two-massive-black-holes
Call for British Museum to take Bayeux tapestry to ‘1066 country’
MP calls for region where Battle of Hastings took place to be included in events surrounding return of artwork
Nadia Khomami Arts and culture correspondent
https://www.theguardian.com/world/2025/jul/14/call-for-british-museum-to-take-bayeux-tapestry-to-1066-country
Futra Days review – esoteric sci-fi romance offers lovers time-jump ‘happiness heists’ to save relationships
A man gets catapulted into the future to help him understand the future of his crush, but the sloppy chronology and gratuitous stylistic touches leave this film a little too infatuated with itself
Phil Hoad
https://www.theguardian.com/film/2025/jul/14/futra-days-review-esoteric-time-travel-romance-loses-its-thread ( Read more... )
An Alarming Lack Of Alarm, Part 5
Jul. 14th, 2025 12:30 pm![[syndicated profile]](https://www.dreamwidth.org/img/silk/identity/feed.png)
Read An Alarming Lack Of Alarm, Part 5
One day, the fire alarm went off. No warning, it just started howling. I'm the designated fire safety guy on our staff, and I have drilled the students (and staff) to exit calmly whenever this happens, using THE NEAREST EXIT. This is important, otherwise we end up having 350 people all trying to leave by the main exit, which will increase the time it takes for everybody to exit the building, up to fifteen minutes instead of less than two.